BDBM50199857 TRIPTOPHENOLIDE

SMILES [H][C@@]12CCc3c(O)c(ccc3[C@@]1(C)CCC1=C2COC1=O)C(C)C

InChI Key InChIKey=KPXIBWGPZSPABK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50199857   

TargetAndrogen receptor(Rat)
Chinese Academy of Medical Science

Curated by ChEMBL
LigandPNGBDBM50199857(TRIPTOPHENOLIDE)
Affinity DataIC50: 467nMAssay Description:Displacement of fluormone-DHT green from His/GST-tagged rat AR ligand binding domain after 4 to 8 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2018
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chinese Academy of Medical Science

Curated by ChEMBL
LigandPNGBDBM50199857(TRIPTOPHENOLIDE)
Affinity DataIC50: 260nMAssay Description:Antagonist activity at wild type AR in human PC3 cells assessed as suppression of DHT-induced receptor transcriptional activation after 24 hrs by PSA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2018
Entry Details Article
PubMed