BDBM50199775 3-(4-((R)-3-(4-ethyl-2-(thiophen-2-yl)phenoxy)butoxy)-2-methylphenyl)propanoic acid::CHEMBL241078

SMILES CCc1ccc(O[C@H](C)CCOc2ccc(CCC(O)=O)c(C)c2)c(c1)-c1cccs1

InChI Key InChIKey=GILNREMWBDGIQX-UHFFFAOYSA-N

Data  9 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50199775   

LigandPNGBDBM50199775(3-(4-((R)-3-(4-ethyl-2-(thiophen-2-yl)phenoxy)buto...)
Affinity DataIC50: 9nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl butyric acid from human PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50199775(3-(4-((R)-3-(4-ethyl-2-(thiophen-2-yl)phenoxy)buto...)
Affinity DataEC50:  2.69E+3nMAssay Description:Agonist activity at human Gal4-PPARalpha expressed in CV1 cells by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50199775(3-(4-((R)-3-(4-ethyl-2-(thiophen-2-yl)phenoxy)buto...)
Affinity DataIC50: 1.09E+3nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-[porpyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-propyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50199775(3-(4-((R)-3-(4-ethyl-2-(thiophen-2-yl)phenoxy)buto...)
Affinity DataEC50:  41nMAssay Description:Agonist activity at human Gal4-PPARdelta expressed in CV1 cells by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50199775(3-(4-((R)-3-(4-ethyl-2-(thiophen-2-yl)phenoxy)buto...)
Affinity DataEC50:  1.99E+3nMAssay Description:Agonist activity at PPARgamma in CV1 cells by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50199775(3-(4-((R)-3-(4-ethyl-2-(thiophen-2-yl)phenoxy)buto...)
Affinity DataIC50: 9.11E+3nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl butyric acid from human PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50199775(3-(4-((R)-3-(4-ethyl-2-(thiophen-2-yl)phenoxy)buto...)
Affinity DataIC50: 9nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50199775(3-(4-((R)-3-(4-ethyl-2-(thiophen-2-yl)phenoxy)buto...)
Affinity DataIC50: 1.09E+3nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50199775(3-(4-((R)-3-(4-ethyl-2-(thiophen-2-yl)phenoxy)buto...)
Affinity DataIC50: 9.11E+3nMAssay Description:Agonist activity at PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50199775(3-(4-((R)-3-(4-ethyl-2-(thiophen-2-yl)phenoxy)buto...)
Affinity DataIC50: 9nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50199775(3-(4-((R)-3-(4-ethyl-2-(thiophen-2-yl)phenoxy)buto...)
Affinity DataIC50: 1.09E+3nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50199775(3-(4-((R)-3-(4-ethyl-2-(thiophen-2-yl)phenoxy)buto...)
Affinity DataIC50: 9.12E+3nMAssay Description:Agonist activity at PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed