BDBM50199759 CHEMBL411759::N-((S,E)-1-(2-((3S)-2-hydroxy-5-oxo-tetrahydrofuran-3-ylamino)-2-oxoethyl)-2-oxo-6-(phenylsulfonamidomethyl)-2,3,4,7-tetrahydro-1H-azepin-3-yl)-2-naphthamide

SMILES OC1OC(=O)C[C@@H]1NC(=O)CN1CC(CNS(=O)(=O)c2ccccc2)=CC[C@H](NC(=O)c2ccc3ccccc3c2)C1=O

InChI Key InChIKey=UIYYZKYDLKUXII-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50199759   

TargetCaspase-3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199759(N-((S,E)-1-(2-((3S)-2-hydroxy-5-oxo-tetrahydrofura...)
Affinity DataIC50: 6.81E+3nMAssay Description:Inhibition of caspase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199759(N-((S,E)-1-(2-((3S)-2-hydroxy-5-oxo-tetrahydrofura...)
Affinity DataIC50: 3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199759(N-((S,E)-1-(2-((3S)-2-hydroxy-5-oxo-tetrahydrofura...)
Affinity DataIC50: 109nMAssay Description:Inhibition of caspase 8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed