BDBM50199758 2,5-dichloro-N-((S,Z)-1-(2-((3S)-2-hydroxy-5-oxotetrahydrofuran-3-ylamino)-2-oxoethyl)-2-oxo-2,3,4,7-tetrahydro-1H-azepin-3-yl)benzamide::CHEMBL242727

SMILES OC1OC(=O)C[C@@H]1NC(=O)CN1CC=CC[C@H](NC(=O)c2cc(Cl)ccc2Cl)C1=O

InChI Key InChIKey=YAXZZOWMNVKCTF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50199758   

TargetCaspase-3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199758(2,5-dichloro-N-((S,Z)-1-(2-((3S)-2-hydroxy-5-oxote...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of caspase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199758(2,5-dichloro-N-((S,Z)-1-(2-((3S)-2-hydroxy-5-oxote...)
Affinity DataIC50: 554nMAssay Description:Inhibition of caspase 8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199758(2,5-dichloro-N-((S,Z)-1-(2-((3S)-2-hydroxy-5-oxote...)
Affinity DataIC50: 15nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed