BDBM50199667 CHEMBL394135::trans-4-(8-amino-1-(3-(benzyloxy)phenyl)imidazo[1,5-a]pyrazin-3-yl)cyclohexanecarboxamide

SMILES NC(=O)[C@H]1CC[C@@H](CC1)c1nc(-c2cccc(OCc3ccccc3)c2)c2c(N)nccn12

InChI Key InChIKey=UVIQXTHQSWQJHO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50199667   

TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199667(trans-4-(8-amino-1-(3-(benzyloxy)phenyl)imidazo[1,...)
Affinity DataIC50: 898nMAssay Description:Inhibition of IGF1-stimulated phosphorylation of human recombinant IGF1R expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199667(trans-4-(8-amino-1-(3-(benzyloxy)phenyl)imidazo[1,...)
Affinity DataIC50: 898nMAssay Description:Inhibition of IGF1-stimulated phosphorylation of human recombinant IGF1R expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199667(trans-4-(8-amino-1-(3-(benzyloxy)phenyl)imidazo[1,...)
Affinity DataIC50: 900nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed