BDBM50199410 CHEMBL3933968::US10131658, Compound 205

SMILES Cc1cccc(NCCCC(=O)Nc2ccc(C[C@H](NC(=O)[C@@H]3CCCN3S(=O)(=O)c3ccccc3)C(O)=O)cc2)n1

InChI Key InChIKey=VMXDSWMLXPSSCM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50199410   

TargetIntegrin alpha-V/beta-1(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50199410(CHEMBL3933968 | US10131658, Compound 205)
Affinity DataIC50: 200nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2018
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-1(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50199410(CHEMBL3933968 | US10131658, Compound 205)
Affinity DataIC50: 200nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2018
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1 [T112H](Human)
University of California

US Patent
LigandPNGBDBM50199410(CHEMBL3933968 | US10131658, Compound 205)
Affinity DataIC50: 505nMAssay Description:A panel of cell lines and integrin ligands were developed to allow rapid examination of potency and specificity of inhibitors against all 8 integrins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
Go to US Patent