BDBM50198847 3-[(2S,4S)-4-(5-fluoro-1-indolinyl)-2-pyrrolidinylcarbonyl]-1,3-thiazolidine::CHEMBL223914

SMILES Fc1ccc2N(CCc2c1)[C@@H]1CN[C@@H](C1)C(=O)N1CCSC1

InChI Key InChIKey=OQIOHISFOWDJQG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50198847   

TargetDipeptidyl peptidase 4(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50198847(3-[(2S,4S)-4-(5-fluoro-1-indolinyl)-2-pyrrolidinyl...)
Affinity DataIC50: 10.1nMAssay Description:Inhibition of DPP4 in rat plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50198847(3-[(2S,4S)-4-(5-fluoro-1-indolinyl)-2-pyrrolidinyl...)
Affinity DataIC50: 563nMAssay Description:Inhibition of human recombinant DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50198847(3-[(2S,4S)-4-(5-fluoro-1-indolinyl)-2-pyrrolidinyl...)
Affinity DataIC50: 519nMAssay Description:Inhibition of human recombinant DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50198847(3-[(2S,4S)-4-(5-fluoro-1-indolinyl)-2-pyrrolidinyl...)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed