BDBM50198769 CHEBI:72761::TRYPROSTATIN A

SMILES [H][C@@]12CCCN1C(=O)[C@]([H])(Cc1c(CC=C(C)C)[nH]c3cc(OC)ccc13)NC2=O

InChI Key InChIKey=XNRPVPHNDQHWLJ-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50198769   

TargetCDGSH iron-sulfur domain-containing protein 1(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM50198769(CHEBI:72761 | TRYPROSTATIN A)
Affinity DataIC50: 3.39E+3nMAssay Description:Displacement of [3H]rosiglitazone from recombinant human C-terminal His-tagged MitoNEET cytosolic domain (32 to 108 residues) expressed in Escherichi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2018
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Guangxi University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50198769(CHEBI:72761 | TRYPROSTATIN A)
Affinity DataKd:  1nMAssay Description:Binding affinity to full length human LXRalpha assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetCDGSH iron-sulfur domain-containing protein 1(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM50198769(CHEBI:72761 | TRYPROSTATIN A)
Affinity DataKi:  145nMAssay Description:Displacement of [3H]rosiglitazone from recombinant human C-terminal His-tagged MitoNEET cytosolic domain (32 to 108 residues) expressed in Escherichi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2018
Entry Details Article
PubMed