BDBM50198626 CHEMBL3950384

SMILES COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc3cc[nH]c3c2)ccc1O

InChI Key InChIKey=SIABTKWBOMYBGS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50198626   

TargetMicrotubule-associated protein tau(Human)
Doshisha University

Curated by ChEMBL
LigandPNGBDBM50198626(CHEMBL3950384)
Affinity DataIC50: 440nMAssay Description:Inhibition of recombinant human TAU three-repeat microtubule-binding domain aggregation expressed in Escherichia coli after 16 hrs by thioflavin T fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2018
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50198626(CHEMBL3950384)
Affinity DataIC50: 420nMAssay Description:Inhibition of amyloid-beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMicrotubule-associated protein tau(Human)
Doshisha University

Curated by ChEMBL
LigandPNGBDBM50198626(CHEMBL3950384)
Affinity DataIC50: 440nMAssay Description:Inhibition of tau phosphorylation (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed