BDBM50198569 (6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-2,3,6,7,12,12a-hexahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione::CHEMBL247073

SMILES COc1ccc(cc1)N1CC(=O)N2[C@H](Cc3c([nH]c4ccccc34)[C@H]2c2ccc3OCOc3c2)C1=O

InChI Key InChIKey=JRXWLWNUSHLDTI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198569   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Inserm U761 Biostructures and Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198569((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-(4-methoxy-phe...)
Affinity DataIC50: 16nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50198569((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-(4-methoxy-phe...)
Affinity DataIC50: 16nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed