BDBM50198377 CHEMBL389422::N-(2,6-dimethylphenyl)-5-[3-(1-methylpiperidin-3-ylmethoxy)phenyl]imidazo[1,5-a]pyrazin-8-amine

SMILES CN1CCCC(COc2cccc(c2)-c2cnc(Nc3c(C)cccc3C)c3cncn23)C1

InChI Key InChIKey=CMZVYJMYCACHOM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198377   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198377(N-(2,6-dimethylphenyl)-5-[3-(1-methylpiperidin-3-y...)
Affinity DataIC50: 740nMAssay Description:Inhibition of cSrc in COS7 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198377(N-(2,6-dimethylphenyl)-5-[3-(1-methylpiperidin-3-y...)
Affinity DataIC50: 19nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed