BDBM50198285 1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperidine-4-carbonitrile::CHEMBL246230

SMILES Clc1ccc(cc1)C1(CCN(Cc2c[nH]c3ccccc23)CC1)C#N

InChI Key InChIKey=XWQQVXPJZWZEFN-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50198285   

TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198285(1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperi...)
Affinity DataEC50:  225nMAssay Description:Antagonist activity at human dopamine D2 receptor expressed in CHO cells assessed as inhibition of quinpirole stimulated mitogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198285(1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperi...)
Affinity DataKi:  199nMAssay Description:Displacement of [125I]IABN from human dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198285(1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperi...)
Affinity DataKi:  684nMAssay Description:Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198285(1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperi...)
Affinity DataKi:  2.27E+3nMAssay Description:Displacement of [125I]IABN from human dopamine D4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed