BDBM50198280 4-(4-chlorophenyl)-1-((1-methyl-1H-indol-3-yl)methyl)piperidin-4-ol::CHEMBL400827

SMILES Cn1cc(CN2CCC(O)(CC2)c2ccc(Cl)cc2)c2ccccc12

InChI Key InChIKey=MKCVGRWVINXSAR-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50198280   

TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198280(4-(4-chlorophenyl)-1-((1-methyl-1H-indol-3-yl)meth...)
Affinity DataEC50:  98.6nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in CHO cells assessed as inhibition of quinpirole stimulated mitogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198280(4-(4-chlorophenyl)-1-((1-methyl-1H-indol-3-yl)meth...)
Affinity DataEC50:  20nMAssay Description:Antagonist activity at human dopamine D2 receptor expressed in CHO cells assessed as inhibition of quinpirole stimulated mitogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198280(4-(4-chlorophenyl)-1-((1-methyl-1H-indol-3-yl)meth...)
Affinity DataKi:  29.6nMAssay Description:Displacement of [125I]IABN from human dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198280(4-(4-chlorophenyl)-1-((1-methyl-1H-indol-3-yl)meth...)
Affinity DataKi:  238nMAssay Description:Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198280(4-(4-chlorophenyl)-1-((1-methyl-1H-indol-3-yl)meth...)
Affinity DataKi:  5.14E+3nMAssay Description:Displacement of [125I]IABN from human dopamine D4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed