BDBM50198270 4-(4-chlorophenyl)-1-((2-methyl-1H-indol-3-yl)methyl)piperidin-4-ol::CHEMBL246439

SMILES Cc1[nH]c2ccccc2c1CN1CCC(O)(CC1)c1ccc(Cl)cc1

InChI Key InChIKey=CMIREZHKYCLJMD-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50198270   

TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198270(4-(4-chlorophenyl)-1-((2-methyl-1H-indol-3-yl)meth...)
Affinity DataEC50:  20.2nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in CHO cells assessed as inhibition of quinpirole stimulated mitogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198270(4-(4-chlorophenyl)-1-((2-methyl-1H-indol-3-yl)meth...)
Affinity DataEC50:  2.13nMAssay Description:Antagonist activity at human dopamine D2 receptor expressed in CHO cells assessed as inhibition of quinpirole stimulated mitogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198270(4-(4-chlorophenyl)-1-((2-methyl-1H-indol-3-yl)meth...)
Affinity DataKi:  15.4nMAssay Description:Displacement of [125I]IABN from human dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198270(4-(4-chlorophenyl)-1-((2-methyl-1H-indol-3-yl)meth...)
Affinity DataKi:  44.1nMAssay Description:Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198270(4-(4-chlorophenyl)-1-((2-methyl-1H-indol-3-yl)meth...)
Affinity DataKi:  2.99E+3nMAssay Description:Displacement of [125I]IABN from human dopamine D4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed