BDBM50198135 (S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-aminothiazol-4-yl)-4-(4-phenylpiperidin-1-yl)butanamide::CHEMBL230507

SMILES Nc1nc(cs1)[C@H](CCN1CCC(CC1)c1ccccc1)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=QMTYTDODWBWULC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198135   

TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198135((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-aminot...)
Affinity DataIC50: 13.3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198135((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-aminot...)
Affinity DataIC50: 13.3nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed