BDBM50198121 2-(2-amino-1,3-thiazol-4-yl)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-4-[(5'R)-5'-methylspiro[indene-1,4'-piperidine]-1'-yl]butanamide::CHEMBL229316

SMILES C[C@H]1CN(CCC(C(=O)NCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2csc(N)n2)CCC11C=Cc2ccccc12

InChI Key InChIKey=RWMKRGFJHUIINF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198121   

TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198121(2-(2-amino-1,3-thiazol-4-yl)-N-{[3,5-bis(trifluoro...)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed