BDBM50198110 CHEMBL388869::N-{4-[1-({[3,5-bis(trifluoromethyl)phenyl]methyl}carbamoyl)-3-[(1S,5'R)-5'-methylspiro[indene-1,4'-piperidine]-1'-yl]propyl]-1,3-thiazol-2-yl}benzamide

SMILES C[C@H]1CN(CCC(C(=O)NCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2csc(NC(=O)c3ccccc3)n2)CC[C@]11C=Cc2ccccc12

InChI Key InChIKey=DJZGCVPXKKXFCC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198110   

TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198110(N-{4-[1-({[3,5-bis(trifluoromethyl)phenyl]methyl}c...)
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198110(N-{4-[1-({[3,5-bis(trifluoromethyl)phenyl]methyl}c...)
Affinity DataIC50: 952nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed