BDBM50198039 CHEMBL374377::[(R)-1-(4'-fluoro-biphenyl-4-sulfonylamino)-2-methyl-propyl]-phosphonic acid

SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(F)cc1)P(O)(O)=O

InChI Key InChIKey=VWKXFDZWHLCIIU-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50198039   

TargetMatrix metalloproteinase-14(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198039([(R)-1-(4'-fluoro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 32nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198039([(R)-1-(4'-fluoro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 59nMAssay Description:Inhibition of human recombinant MMP9 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198039([(R)-1-(4'-fluoro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198039([(R)-1-(4'-fluoro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 160nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198039([(R)-1-(4'-fluoro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 150nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198039([(R)-1-(4'-fluoro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198039([(R)-1-(4'-fluoro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198039([(R)-1-(4'-fluoro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 13nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed