BDBM50198030 CHEMBL228188::[(R)-1-(3'-chloro-biphenyl-4-sulfonylamino)-2-methyl-propyl]-phosphonic acid

SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1cccc(Cl)c1)P(O)(O)=O

InChI Key InChIKey=BGBWSADVPWNBME-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50198030   

TargetMatrix metalloproteinase-9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198030([(R)-1-(3'-chloro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant MMP9 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198030([(R)-1-(3'-chloro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 75nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198030([(R)-1-(3'-chloro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 24nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198030([(R)-1-(3'-chloro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198030([(R)-1-(3'-chloro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198030([(R)-1-(3'-chloro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198030([(R)-1-(3'-chloro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 320nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198030([(R)-1-(3'-chloro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 440nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed