BDBM50197970 CHEMBL3913521

SMILES [H][C@]12CC\C(C)=C\C[C@@]3(CC[C@@](C)(O3)[C@H](CC[C@@]1(C)O2)OC(C)=O)C(C)C

InChI Key InChIKey=QYKARXZAAXHOJT-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50197970   

TargetHeat sensitive channel TRPV3(Rat)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50197970(CHEMBL3913521)
Affinity DataIC50: 2.11E+4nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50197970(CHEMBL3913521)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetHeat sensitive channel TRPV3(Rat)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50197970(CHEMBL3913521)
Affinity DataEC50:  8.60E+3nMAssay Description:Activation of rat TRPV3 overexpressed in HEK293 cells assessed as increase in 2-aminoethoxydiphenyl borate-induced intracellular calcium concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed