BDBM50197929 CHEMBL3954506

SMILES [O-][N+](=O)c1cccc(Nc2nc(NC3CCCCC3)nc(n2)C#N)c1

InChI Key InChIKey=BPWNJPXVAFVVPP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50197929   

TargetCathepsin K(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50197929(CHEMBL3954506)
Affinity DataIC50: 17nMAssay Description:Inhibition of human cathepsin K expressed in Pichia pastoris using Z-Phe-Arg-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50197929(CHEMBL3954506)
Affinity DataIC50: 23nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCathepsin S(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50197929(CHEMBL3954506)
Affinity DataIC50: 28nMAssay Description:Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCathepsin B(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50197929(CHEMBL3954506)
Affinity DataIC50: 79nMAssay Description:Inhibition of human cathepsin B using Z-Phe-Arg-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed