BDBM50197923 CHEMBL3962225

SMILES [O-][N+](=O)c1ccc(Nc2nc(nc(n2)N2CCNCC2)C#N)cc1

InChI Key InChIKey=KYELOXDGOIUIAM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50197923   

TargetCathepsin K(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50197923(CHEMBL3962225)
Affinity DataIC50: 17nMAssay Description:Inhibition of human cathepsin K expressed in Pichia pastoris using Z-Phe-Arg-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50197923(CHEMBL3962225)
Affinity DataIC50: 17nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCathepsin S(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50197923(CHEMBL3962225)
Affinity DataIC50: 23nMAssay Description:Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectromicrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed