BDBM50197900 CHEMBL223336::N-(1-(4-fluorobenzyl)pyrrolidin-3-yl)isoquinolin-5-amine::N-[1-(4-fluorobenzyl)-3-pyrrolidyl]-N-(5-isoquinolyl)amine

SMILES Fc1ccc(CN2CCC(C2)Nc2cccc3cnccc23)cc1

InChI Key InChIKey=WAWIIKAKESUSCT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50197900   

TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50197900(N-[1-(4-fluorobenzyl)-3-pyrrolidyl]-N-(5-isoquinol...)
Affinity DataIC50: 95nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50197900(N-[1-(4-fluorobenzyl)-3-pyrrolidyl]-N-(5-isoquinol...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of MCP1-induced chemotaxis in U937 cells overexpressing CCR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed