BDBM50197879 CHEMBL3972214

SMILES Oc1cccc2ccc(CN(CC#C)C(CC3CCN(Cc4ccccc4)CC3)C#N)nc12

InChI Key InChIKey=MFWCFENQSTYMSU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50197879   

TargetAmine oxidase [flavin-containing] A(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197879(CHEMBL3972214)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197879(CHEMBL3972214)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197879(CHEMBL3972214)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant BuChE expressed in HEK293 cells using S-butyrylthiocholine iodide as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197879(CHEMBL3972214)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAOB using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed