BDBM50197713 CHEMBL3947281

SMILES Nc1c(cnn1-c1cc(O)ccc1Cl)C(=O)c1ccc2ncccc2c1

InChI Key InChIKey=FPKUEZLSSIDWJS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50197713   

TargetVascular endothelial growth factor receptor 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197713(CHEMBL3947281)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human KDR by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197713(CHEMBL3947281)
Affinity DataIC50: 720nMAssay Description:Inhibition of human FGFR3 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197713(CHEMBL3947281)
Affinity DataIC50: 230nMAssay Description:Inhibition of human FGFR2 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197713(CHEMBL3947281)
Affinity DataIC50: 31nMAssay Description:Inhibition of human SRC by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197713(CHEMBL3947281)
Affinity DataIC50: 450nMAssay Description:Inhibition of human FGFR1 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 4(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197713(CHEMBL3947281)
Affinity DataIC50: 740nMAssay Description:Inhibition of human FGFR4 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMed