BDBM50197667 CHEMBL3968927

SMILES CC1(CCS(=O)(=O)CC1)[C@@H]1CN(CCOc2ccc(F)c(c2)C#N)C(=O)C1

InChI Key InChIKey=SYEMWCXBADSSGE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50197667   

TargetPlatelet-activating factor acetylhydrolase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197667(CHEMBL3968927)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of recombinant human Lp-PLA2 pre-incubated for 30 mins before PED6 fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197667(CHEMBL3968927)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of Lp-PLA2 in whole human plasma pre-incubated for 15 mins before 2-thio-PAF substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMed