BDBM50197652 CHEMBL3943407

SMILES CC(C)[C@]1(C)CN(CCOc2ccc(F)c(c2)C#N)C(=O)C1

InChI Key InChIKey=RDZCOUPVSMBOAC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50197652   

TargetPlatelet-activating factor acetylhydrolase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197652(CHEMBL3943407)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of Lp-PLA2 in whole human plasma pre-incubated for 15 mins before 2-thio-PAF substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197652(CHEMBL3943407)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of recombinant human Lp-PLA2 incubated for 20 mins by Thio-PAF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMed