BDBM50197420 (2S,3R,5R)-5-[(hydrogen phosphonatooxy)methyl]-2-(hydroxymethyl)-3-(4-octylphenyl)pyrrolidin-1-ium::CHEMBL393055

SMILES CCCCCCCCc1ccc(cc1)[C@H]1C[C@H](COP(O)([O-])=O)[NH2+][C@@H]1CO

InChI Key InChIKey=DKHSWCUVNLYVPR-UHFFFAOYSA-N

Data  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50197420   

TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50197420((2S,3R,5R)-5-[(hydrogen phosphonatooxy)methyl]-2-(...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at S1P1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50197420((2S,3R,5R)-5-[(hydrogen phosphonatooxy)methyl]-2-(...)
Affinity DataEC50:  10.2nMAssay Description:Agonist activity at S1P5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50197420((2S,3R,5R)-5-[(hydrogen phosphonatooxy)methyl]-2-(...)
Affinity DataEC50:  7.40nMAssay Description:Agonist activity at S1P4 receptor in human U2OS cells expressing VP16-GAL4 transcriptional factor and beta-arrestin/TEV protease fusion protein asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50197420((2S,3R,5R)-5-[(hydrogen phosphonatooxy)methyl]-2-(...)
Affinity DataEC50: >1.00E+3nMAssay Description:Activity at human recombinant S1P3 receptor expressed in CHO cells assessed as increase in calcium release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50197420((2S,3R,5R)-5-[(hydrogen phosphonatooxy)methyl]-2-(...)
Affinity DataEC50:  7.40nMAssay Description:Activity at human recombinant S1P4 receptor expressed in CHO cells assessed as increase in calcium release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50197420((2S,3R,5R)-5-[(hydrogen phosphonatooxy)methyl]-2-(...)
Affinity DataEC50:  10.2nMAssay Description:Activity at human recombinant S1P5 receptor expressed in CHO cells assessed as increase in calcium release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50197420((2S,3R,5R)-5-[(hydrogen phosphonatooxy)methyl]-2-(...)
Affinity DataEC50: >1.00E+3nMAssay Description:Activity at human recombinant S1P1 receptor expressed in CHO cells assessed as increase in calcium release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed