BDBM50197409 2-(2-chloro-4-fluoro-phenoxy)-N-(5-ethanesulfonyl-adamantan-2-yl)-2-methyl-propionamide::CHEMBL241709

SMILES CCS(=O)(=O)[C@@]12CC3CC(C1)[C@H](NC(=O)C(C)(C)Oc1ccc(F)cc1Cl)C(C3)C2

InChI Key

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50197409   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197409(2-(2-chloro-4-fluoro-phenoxy)-N-(5-ethanesulfonyl-...)
Affinity DataIC50: 450nMAssay Description:Inhibition of human HSD1 expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197409(2-(2-chloro-4-fluoro-phenoxy)-N-(5-ethanesulfonyl-...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human HSD2 assessed as interconversion of cortisone to cortisolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197409(2-(2-chloro-4-fluoro-phenoxy)-N-(5-ethanesulfonyl-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse HSD2 assessed as interconversion of cortisone to cortisolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197409(2-(2-chloro-4-fluoro-phenoxy)-N-(5-ethanesulfonyl-...)
Affinity DataKi:  7nMAssay Description:Inhibition of mouse HSD1 assessed as interconversion of cortisone to cortisolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197409(2-(2-chloro-4-fluoro-phenoxy)-N-(5-ethanesulfonyl-...)
Affinity DataKi:  26nMAssay Description:Inhibition of human HSD1 assessed as interconversion of cortisone to cortisolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed