BDBM50197324 4-({[(1S)-(aminocarbonyl)-3-methylbutyl]amino}-carbonyl)-2'-({[4-(aminomethyl)phenyl]amino}carbonyl)-4'-(methylamino)biphenyl-2-carboxylic acid::CHEMBL426187

SMILES CNc1ccc(c(c1)C(=O)Nc1ccc(CN)cc1)-c1ccc(cc1C(O)=O)C(=O)N[C@@H](CC(C)C)C(N)=O

InChI Key InChIKey=HZXXCUHFMZWQSC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50197324   

TargetCoagulation factor VII/Tissue factor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197324(4-({[(1S)-(aminocarbonyl)-3-methylbutyl]amino}-car...)
Affinity DataIC50: 590nMAssay Description:Inhibition of human TF/FVIIa complex by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197324(4-({[(1S)-(aminocarbonyl)-3-methylbutyl]amino}-car...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197324(4-({[(1S)-(aminocarbonyl)-3-methylbutyl]amino}-car...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human Fxa by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed