BDBM50197236 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(morpholinosulfonyl)piperidine-4-carboxamide::CHEMBL231666

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)N1CCOCC1)C(=O)NO

InChI Key InChIKey=DUPLEMOAJXTDKP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50197236   

Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197236(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 51nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197236(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 195nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50197236(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 1nMAssay Description:Inhibition of TACE in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed