BDBM50197230 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(5-chlorothiophen-2-ylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL234775

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)c1ccc(Cl)s1)C(=O)NO

InChI Key InChIKey=JOILTJHUYYDODY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50197230   

LigandPNGBDBM50197230(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(5-c...)
Affinity DataIC50: 7nMAssay Description:Inhibition of TACE in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197230(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(5-c...)
Affinity DataIC50: 33nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed