BDBM50197217 CHEMBL400206::N-(3-(1-tert-butylpiperidin-4-yl)-1-(4-((2-methylquinolin-4-yl)methoxy)phenylsulfonyl)propan-2-yl)-N-hydroxyformamide

SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(CC2CCN(CC2)C(C)(C)C)N(O)C=O)c2ccccc2n1

InChI Key InChIKey=BUDIJDXJWOVXRJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50197217   

TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197217(N-(3-(1-tert-butylpiperidin-4-yl)-1-(4-((2-methylq...)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197217(N-(3-(1-tert-butylpiperidin-4-yl)-1-(4-((2-methylq...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197217(N-(3-(1-tert-butylpiperidin-4-yl)-1-(4-((2-methylq...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197217(N-(3-(1-tert-butylpiperidin-4-yl)-1-(4-((2-methylq...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50197217(N-(3-(1-tert-butylpiperidin-4-yl)-1-(4-((2-methylq...)
Affinity DataIC50: 12nMAssay Description:Inhibition of TACE in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed