BDBM50197195 3-((2-phenethylphenoxy)methyl)pyridine::3-{[2-(2-phenylethyl)phenoxy]methyl}pyridine::CHEMBL217425

SMILES C(Cc1ccccc1OCc1cccnc1)c1ccccc1

InChI Key InChIKey=WUVSQVHZKKJEHX-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50197195   

TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50197195(3-{[2-(2-phenylethyl)phenoxy]methyl}pyridine | 3-(...)
Affinity DataEC50:  1.25E+5nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50197195(3-{[2-(2-phenylethyl)phenoxy]methyl}pyridine | 3-(...)
Affinity DataEC50:  1.25E+5nMAssay Description:Inhibition of Pgp measured as inhibition of [3H]vinblastine basolateral to apical transport in Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50197195(3-{[2-(2-phenylethyl)phenoxy]methyl}pyridine | 3-(...)
Affinity DataKi:  5.00E+3nMAssay Description:Binding affinity to D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50197195(3-{[2-(2-phenylethyl)phenoxy]methyl}pyridine | 3-(...)
Affinity DataKi:  5.00E+3nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed