BDBM50197143 CHEMBL277531::N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-7-chloro-3-methyl-4-oxo-4H-chromene-2-carboxamide

SMILES Cc1c(oc2cc(Cl)ccc2c1=O)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1

InChI Key InChIKey=CKLKYZJYRNDNQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50197143   

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197143(N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-7...)
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197143(N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-7...)
Affinity DataIC50: 67nMAssay Description:Antagonist activity at MCHr1 assessed as inhibition of MCH-mediated calcium ion release in intact IMR32 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed