BDBM50197141 CHEMBL216680::N-(1-(4-acetamidobenzyl)piperidin-4-yl)-7-fluoro-4-oxo-4H-chromene-2-carboxamide::N-[1-N-[1-{4-[(4-aminopiperidin-1-yl)methyl]phenyl}ethanonyl]-7-fluoro-4-oxo-4H-chromene-2-carboxamide

SMILES CC(=O)Nc1ccc(CN2CCC(CC2)NC(=O)c2cc(=O)c3ccc(F)cc3o2)cc1

InChI Key InChIKey=AXOYDNAEBFRXFX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50197141   

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197141(N-[1-N-[1-{4-[(4-aminopiperidin-1-yl)methyl]phenyl...)
Affinity DataIC50: 1.69E+3nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197141(N-[1-N-[1-{4-[(4-aminopiperidin-1-yl)methyl]phenyl...)
Affinity DataIC50: 47.7nMAssay Description:Displacement of [3H]dofetilide from hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197141(N-[1-N-[1-{4-[(4-aminopiperidin-1-yl)methyl]phenyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at MCHr1 assessed as inhibition of MCH-mediated calcium ion release in intact IMR32 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197141(N-[1-N-[1-{4-[(4-aminopiperidin-1-yl)methyl]phenyl...)
Affinity DataIC50: 4.77E+4nMAssay Description:Displacement of 3H-dofetilide from hERG-expressing HEK membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197141(N-[1-N-[1-{4-[(4-aminopiperidin-1-yl)methyl]phenyl...)
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed