BDBM50197132 CHEMBL384487::N-[1-{4-[(4-aminopiperidin-1-yl)methyl]phenyl}ethanonyl]-7-fluoro-4-oxo-4H-chromene-2-carboxamide

SMILES CC(=O)c1ccc(CN2CCC(CC2)NC(=O)c2cc(=O)c3ccc(F)cc3o2)cc1

InChI Key InChIKey=ZZCFQOGPJUCWRJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50197132   

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197132(N-[1-{4-[(4-aminopiperidin-1-yl)methyl]phenyl}etha...)
Affinity DataIC50: 39nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197132(N-[1-{4-[(4-aminopiperidin-1-yl)methyl]phenyl}etha...)
Affinity DataIC50: 20.3nMAssay Description:Displacement of [3H]dofetilide from hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197132(N-[1-{4-[(4-aminopiperidin-1-yl)methyl]phenyl}etha...)
Affinity DataIC50: 581nMAssay Description:Antagonist activity at MCHr1 assessed as inhibition of MCH-mediated calcium ion release in intact IMR32 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed