BDBM50197114 CHEMBL214767::N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-4-oxo-4H-chromene-2-carboxamide

SMILES O=C(NC1CCN(Cc2ccc3OCOc3c2)CC1)c1cc(=O)c2ccccc2o1

InChI Key InChIKey=IZLJKNPYMLZCPG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50197114   

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197114(N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-4...)
Affinity DataIC50: 66nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197114(N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-4...)
Affinity DataIC50: 192nMAssay Description:Antagonist activity at MCHr1 assessed as inhibition of MCH-mediated calcium ion release in intact IMR32 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197114(N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-4...)
Affinity DataIC50: 6.70nMAssay Description:Displacement of [3H]dofetilide from hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed