BDBM50197113 CHEMBL214731::N-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-yl)-6-fluoro-4-oxo-4H-chromene-2-carboxamide::N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-6-fluoro-4-oxo-4H-chromene-2-carboxamide

SMILES Fc1ccc2oc(cc(=O)c2c1)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1

InChI Key InChIKey=HHCYCBKPWYJVEB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50197113   

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197113(N-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-y...)
Affinity DataIC50: 65nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197113(N-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-y...)
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]dofetilide from hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197113(N-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-y...)
Affinity DataIC50: 196nMAssay Description:Antagonist activity at MCHr1 assessed as inhibition of MCH-mediated calcium ion release in intact IMR32 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197113(N-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-y...)
Affinity DataIC50: 1.50E+4nMAssay Description:Displacement of 3H-dofetilide from hERG-expressing HEK membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197113(N-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-y...)
Affinity DataIC50: 4nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed