BDBM50197083 CHEMBL3890846

SMILES ONC(=O)CCCCCc1ccc2OCOc2c1

InChI Key InChIKey=UWTYFMHKFJGRHX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50197083   

TargetHistone deacetylase 1(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50197083(CHEMBL3890846)
Affinity DataIC50: 560nMAssay Description:Inhibition of human recombinant GST-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using MOCPAC as substrate after 4 hrs by UHPLC-ES...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50197083(CHEMBL3890846)
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant HDAC6 expressed in baculovirus infected insect cells using BATCP as substrate after 4 hrs by UHPLC-ESI-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50197083(CHEMBL3890846)
Affinity DataIC50: 973nMAssay Description:Inhibition of HDAC1 in human SHSY5Y cells using MOCPAC as substrate after 8 hrs by UHPLC-ESI-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/2/3(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50197083(CHEMBL3890846)
Affinity DataIC50: 188nMAssay Description:Inhibition of HDAC1/HDAC2/HDAC3 in human HeLa nuclear extracts using MAL as substrate after 4 hrs by UHPLC-ESI-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50197083(CHEMBL3890846)
Affinity DataIC50: 164nMAssay Description:Inhibition of HDAC6 in human SHSY5Y cells using BATCP as substrate after 8 hrs by UHPLC-ESI-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed