BDBM50197067 CHEMBL3913746

SMILES CC(C)(O)CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccnc(Cl)c2)n1

InChI Key InChIKey=AWNXKZVIZARMME-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50197067   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Curtin University

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 76nMAssay Description:Inhibition of Vps34 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3KC2gamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3KC2beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3KC2alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Curtin University

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 25nMAssay Description:Inhibition of Vps34 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human Vps34-Vps15 complex expressed in insect cells assessed as reduction in PtdIns phosphorylation in presence of gamma32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Curtin University

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 25nMAssay Description:Inhibition of VPS34 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed