BDBM50196792 CHEMBL3968418

SMILES CS(=O)(=O)c1ccc(O[C@@H]2[C@H](Cc3ccccc23)N2CCCC2)cc1

InChI Key InChIKey=WWOXYKIVKIDSIX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50196792   

TargetCytochrome P450 2D6(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50196792(CHEMBL3968418)
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP2D6 in pooled human hepatic microsomes using dextromethorphan substrate in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2018
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50196792(CHEMBL3968418)
Affinity DataIC50: 572nMAssay Description:Inhibition of human NHE3 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2018
Entry Details Article
PubMed