BDBM50196685 CHEMBL389622::N-(1-(3,5-dimethoxybenzyl)piperidin-3-yl)-1H-indazol-5-amine::N-[1-(3,5-dimethoxybenzyl)-3-piperidyl]-N-(1H-5-indazolyl)amine

SMILES COc1cc(CN2CCCC(C2)Nc2ccc3[nH]ncc3c2)cc(OC)c1

InChI Key InChIKey=QRVGBTGBMIUBQJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50196685   

TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196685(N-(1-(3,5-dimethoxybenzyl)piperidin-3-yl)-1H-indaz...)
Affinity DataIC50: 80nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196685(N-(1-(3,5-dimethoxybenzyl)piperidin-3-yl)-1H-indaz...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MCP1-induced cell migration in U937 cells expressing CCR2 by chemotaxis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed