BDBM50196629 (1-(4-chlorophenylsulfonyl)-1,2,3,4-tetrahydroquinolin-2-yl)methyl 1,4'-bipiperidine-1'-carboxylate::(1-(4-chlorophenylsulfonyl)-1,2,3,4-tetrahydroquinolin-2-yl)methyl 4-(piperidin-1-yl)piperidine-1-carboxylate::CHEMBL231250

SMILES Clc1ccc(cc1)S(=O)(=O)N1C(COC(=O)N2CCC(CC2)N2CCCCC2)CCc2ccccc12

InChI Key InChIKey=YSSDLRQAOJLLFT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50196629   

TargetAmyloid-beta precursor protein(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50196629((1-(4-chlorophenylsulfonyl)-1,2,3,4-tetrahydroquin...)
Affinity DataIC50: 73nMAssay Description:Inhibition of gamma-secretaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50196629((1-(4-chlorophenylsulfonyl)-1,2,3,4-tetrahydroquin...)
Affinity DataIC50: 39nMAssay Description:Inhibition of Gamma-secretaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50196629((1-(4-chlorophenylsulfonyl)-1,2,3,4-tetrahydroquin...)
Affinity DataIC50: 39nMAssay Description:Inhibition of Gamma-secretaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50196629((1-(4-chlorophenylsulfonyl)-1,2,3,4-tetrahydroquin...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Gamma-secretaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed