BDBM50196580 CHEMBL401338::N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-methoxy-benzylamino)-propyl]-3-(3-methyl-butylsulfamoyl)-propionamide

SMILES COc1cccc(CNC[C@@H](O)[C@H](Cc2ccccc2)NC(=O)CCS(=O)(=O)NCCC(C)C)c1

InChI Key InChIKey=ADUWXOLELPWYPY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50196580   

TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196580(N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-methoxy-benzyla...)
Affinity DataIC50: 2.12E+3nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196580(N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-methoxy-benzyla...)
Affinity DataIC50: 5.02E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed