BDBM50196382 5-[4-(4-bromo-phenylamino)-phenylamino]-N-cyclohexylmethyl-3-hydroxy-isothiazole-4-carboxamidine::CHEMBL399237

SMILES NC(=NCC1CCCCC1)c1c(Nc2ccc(Nc3ccc(Br)cc3)cc2)s[nH]c1=O

InChI Key InChIKey=ZEJNJBHRJYTVKG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50196382   

TargetSerine/threonine-protein kinase Chk2(Human)
Valeant Pharmaceutical Research and Development 3300 Hyland Avenue

Curated by ChEMBL
LigandPNGBDBM50196382(5-[4-(4-bromo-phenylamino)-phenylamino]-N-cyclohex...)
Affinity DataIC50: 300nMAssay Description:Inhibition of Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed