BDBM50196111 4-(3-methyltetrahydropyrimidin-1(2H)-yl)phenyl]-(2,3,8-trimethylquinolin-4-yl)amine::CHEMBL216072

SMILES CN1CCCN(C1)c1ccc(Nc2c(C)c(C)nc3c(C)cccc23)cc1

InChI Key InChIKey=KUMLVCNUFRRWHR-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50196111   

TargetAlpha-2C adrenergic receptor(Human)
Juvantia Pharma

Curated by ChEMBL
LigandPNGBDBM50196111(4-(3-methyltetrahydropyrimidin-1(2H)-yl)phenyl]-(2...)
Affinity DataKi:  770nMAssay Description:Displacement of [3H]rauwolscine from human ADRA2C expressed in S115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2B adrenergic receptor(Human)
Juvantia Pharma

Curated by ChEMBL
LigandPNGBDBM50196111(4-(3-methyltetrahydropyrimidin-1(2H)-yl)phenyl]-(2...)
Affinity DataKi:  2.50E+3nMAssay Description:Displacement of [3H]rauwolscine from human ADRA2B expressed in S115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Juvantia Pharma

Curated by ChEMBL
LigandPNGBDBM50196111(4-(3-methyltetrahydropyrimidin-1(2H)-yl)phenyl]-(2...)
Affinity DataKi:  5.00E+3nMAssay Description:Binding affinity to human cloned Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Juvantia Pharma

Curated by ChEMBL
LigandPNGBDBM50196111(4-(3-methyltetrahydropyrimidin-1(2H)-yl)phenyl]-(2...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]rauwolscine from human ADRA2A expressed in S115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed