BDBM50195913 4-(2-methyl-quinolin-4-ylmethoxy)-N-(6,8,10-trioxo-7,9-diaza-spiro[4.5]dec-1-yl)-benzamide::CHEMBL247967

SMILES Cc1cc(COc2ccc(cc2)C(=O)NC2CCCC22C(=O)NC(=O)NC2=O)c2ccccc2n1

InChI Key InChIKey=YYHXOYNNTNFXCS-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50195913   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50195913(4-(2-methyl-quinolin-4-ylmethoxy)-N-(6,8,10-trioxo...)
Affinity DataIC50: 24nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50195913(4-(2-methyl-quinolin-4-ylmethoxy)-N-(6,8,10-trioxo...)
Affinity DataKi: >3.33E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed