BDBM50195904 4-(2-methyl-quinolin-4-ylmethoxy)-N-(1,3,5-trioxo-2,4-diaza-spiro[5.5]undec-7-yl)-benzamide::CHEMBL442423

SMILES Cc1cc(COc2ccc(cc2)C(=O)NC2CCCCC22C(=O)NC(=O)NC2=O)c2ccccc2n1

InChI Key InChIKey=ODDQJXJHWIBVKQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50195904   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50195904(4-(2-methyl-quinolin-4-ylmethoxy)-N-(1,3,5-trioxo-...)
Affinity DataIC50: 138nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50195904(4-(2-methyl-quinolin-4-ylmethoxy)-N-(1,3,5-trioxo-...)
Affinity DataKi:  110nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed