BDBM50195008 4-(3-chloro-4-fluorophenylamino)-6-(pyridin-2-ylmethylamino)quinoline-3-carbonitrile::CHEMBL374482

SMILES Fc1ccc(Nc2c(cnc3ccc(NCc4ccccn4)cc23)C#N)cc1Cl

InChI Key InChIKey=BEYSNYOQAFDZBA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50195008   

TargetMitogen-activated protein kinase kinase kinase 8(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50195008(4-(3-chloro-4-fluorophenylamino)-6-(pyridin-2-ylme...)
Affinity DataIC50: 90nMAssay Description:Inhibition of Tpl2 kinase by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed